University of Maryland Greenebaum Cancer Center Mesothelioma: A Comprehensive Overview

Introduction

Welcome to our comprehensive guide on mesothelioma treatment at the University of Maryland Greenebaum Cancer Center. In this article, we will provide an in-depth analysis of mesothelioma, including its causes, symptoms, diagnosis, and treatment options. We will also discuss how the University of Maryland Greenebaum Cancer Center is at the forefront of research and clinical care for mesothelioma patients. Whether you are a patient, caregiver, or healthcare professional, this guide will provide the information and resources you need to navigate this complex disease.

The Reality of Mesothelioma

Mesothelioma is a type of cancer that affects the mesothelial tissue, which lines the lungs, heart, and abdominal cavity. It is typically caused by exposure to asbestos, a naturally occurring mineral that was widely used in construction and manufacturing until the 1970s. Mesothelioma is a particularly aggressive cancer, with a poor prognosis and limited treatment options. According to the American Cancer Society, approximately 3,000 new cases of mesothelioma are diagnosed in the United States each year.

The University of Maryland Greenebaum Cancer Center: A Leader in Mesothelioma Care

The University of Maryland Greenebaum Cancer Center is a National Cancer Institute-designated comprehensive cancer center located in Baltimore, Maryland. The cancer center offers a range of cutting-edge treatments for mesothelioma, including surgery, radiation therapy, chemotherapy, and clinical trials. The mesothelioma program at the University of Maryland Greenebaum Cancer Center is led by Dr. Joseph Friedberg, a renowned mesothelioma surgeon and researcher.

Causes and Risk Factors of Mesothelioma

The primary cause of mesothelioma is exposure to asbestos, a fibrous mineral that was widely used in construction and manufacturing until the 1970s. Asbestos fibers can become trapped in the lungs or other organs, leading to inflammation and the development of cancerous cells. Other risk factors for mesothelioma include smoking, radiation exposure, and genetic predisposition.

Symptoms of Mesothelioma

The symptoms of mesothelioma can be subtle and are often mistaken for other conditions. Common symptoms include shortness of breath, chest pain, coughing, and fatigue. In some cases, mesothelioma can also cause abdominal pain, swelling, and weight loss. If you have been exposed to asbestos or are experiencing any of these symptoms, it is important to seek medical attention as soon as possible.

Diagnosis of Mesothelioma

Diagnosing mesothelioma can be challenging, as the symptoms are often vague and nonspecific. To diagnose mesothelioma, doctors will typically perform a physical exam, imaging tests, and a biopsy of the affected tissue. A biopsy involves removing a small sample of tissue for laboratory analysis to determine the presence of cancerous cells.

Treatment Options for Mesothelioma

The treatment options for mesothelioma depend on the stage and location of the cancer, as well as the patient’s overall health. The University of Maryland Greenebaum Cancer Center offers a range of advanced treatment options, including surgery, radiation therapy, chemotherapy, and clinical trials. Surgery is often the first-line treatment for mesothelioma, with the goal of removing as much of the cancerous tissue as possible. Radiation therapy uses high-energy radiation to kill cancer cells, while chemotherapy uses drugs to destroy cancer cells throughout the body.

Clinical Trials for Mesothelioma

Clinical trials are an important component of mesothelioma research, as they allow doctors and researchers to develop and test new treatments for the disease. The University of Maryland Greenebaum Cancer Center offers a range of clinical trials for mesothelioma, including trials for new chemotherapy drugs, immunotherapy treatments, and surgical techniques. Participating in a clinical trial can provide mesothelioma patients with access to cutting-edge treatments that may not be available elsewhere.

Mesothelioma Treatment at the University of Maryland Greenebaum Cancer Center

The Multidisciplinary Approach to Mesothelioma Care

The University of Maryland Greenebaum Cancer Center takes a multidisciplinary approach to mesothelioma care, with a team of experts from various specialties working together to provide the best possible treatment. The mesothelioma team includes surgeons, medical oncologists, radiation oncologists, pathologists, and other specialists, all of whom have extensive experience in treating mesothelioma.

Surgical Treatment Options for Mesothelioma

The University of Maryland Greenebaum Cancer Center offers a range of surgical treatment options for mesothelioma, including extrapleural pneumonectomy (EPP), pleurectomy/decortication (P/D), and video-assisted thoracoscopy (VATS). EPP involves the removal of the affected lung, pleura, and diaphragm, while P/D involves the removal of the pleura and any visible tumors. VATS is a minimally invasive surgical technique that uses small incisions and a video camera to remove the cancerous tissue.

Radiation Therapy for Mesothelioma

Radiation therapy is often used in combination with surgery and/or chemotherapy to treat mesothelioma. The University of Maryland Greenebaum Cancer Center offers a range of radiation therapy options for mesothelioma, including intensity-modulated radiation therapy (IMRT), stereotactic body radiation therapy (SBRT), and brachytherapy. These advanced techniques allow doctors to deliver high doses of radiation to the cancerous tissue while minimizing damage to the surrounding healthy tissue.

Chemotherapy for Mesothelioma

Chemotherapy is a systemic treatment that uses drugs to destroy cancer cells throughout the body. The University of Maryland Greenebaum Cancer Center offers a range of chemotherapy options for mesothelioma, including cisplatin, carboplatin, pemetrexed, and gemcitabine. These drugs can be administered orally or intravenously, depending on the patient’s individual needs and treatment plan.

Immunotherapy for Mesothelioma

Immunotherapy is a new and promising approach to mesothelioma treatment, which involves using the body’s own immune system to fight cancer cells. The University of Maryland Greenebaum Cancer Center offers a range of immunotherapy options for mesothelioma, including checkpoint inhibitors, CAR-T cell therapy, and cancer vaccines. These treatments are still in the early stages of development, but they have shown promising results in clinical trials.

University of Maryland Greenebaum Cancer Center Mesothelioma Treatment Table

Treatment Type Description
Extrapleural Pneumonectomy (EPP) Removal of affected lung, pleura, and diaphragm
Pleurectomy/Decortication (P/D) Removal of pleura and visible tumors
Video-Assisted Thoracoscopy (VATS) Minimally invasive surgical technique using small incisions and a video camera
Intensity-Modulated Radiation Therapy (IMRT) Delivers high doses of radiation to cancerous tissue while minimizing damage to surrounding healthy tissue
Stereotactic Body Radiation Therapy (SBRT) Highly precise radiation therapy that targets tumors with high doses of radiation
Brachytherapy Uses radioactive seeds to deliver radiation directly to the cancerous tissue
Cisplatin Chemotherapy drug that targets rapidly dividing cancer cells
Carboplatin Chemotherapy drug that targets rapidly dividing cancer cells
Pemetrexed Chemotherapy drug that targets cancer cells by interfering with DNA replication
Gemcitabine Chemotherapy drug that targets rapidly dividing cancer cells
Checkpoint Inhibitors Immunotherapy drugs that block the checkpoints that cancer cells use to evade
the immune system
CAR-T Cell Therapy Immunotherapy technique that involves modifying the patient’s T-cells to attack cancer cells
Cancer Vaccines Immunotherapy approach that involves using vaccines to stimulate the immune system to attack cancer cells

Frequently Asked Questions (FAQs)

What is mesothelioma?

Mesothelioma is a type of cancer that affects the mesothelial tissue, which lines the lungs, heart, and abdominal cavity.

What causes mesothelioma?

Mesothelioma is primarily caused by exposure to asbestos, a naturally occurring mineral that was widely used in construction and manufacturing until the 1970s.

What are the symptoms of mesothelioma?

The symptoms of mesothelioma can include shortness of breath, chest pain, coughing, and fatigue. In some cases, mesothelioma can also cause abdominal pain, swelling, and weight loss.

How is mesothelioma diagnosed?

Diagnosing mesothelioma typically involves a physical exam, imaging tests, and a biopsy of the affected tissue.

What are the treatment options for mesothelioma?

The treatment options for mesothelioma depend on the stage and location of the cancer, as well as the patient’s overall health. Treatment options may include surgery, radiation therapy, chemotherapy, and clinical trials.

What is the University of Maryland Greenebaum Cancer Center?

The University of Maryland Greenebaum Cancer Center is a National Cancer Institute-designated comprehensive cancer center located in Baltimore, Maryland.

What makes the University of Maryland Greenebaum Cancer Center a leader in mesothelioma care?

The University of Maryland Greenebaum Cancer Center offers a range of cutting-edge treatments for mesothelioma, including surgery, radiation therapy, chemotherapy, and clinical trials. The mesothelioma program at the University of Maryland Greenebaum Cancer Center is led by Dr. Joseph Friedberg, a renowned mesothelioma surgeon and researcher.

What is the multidisciplinary approach to mesothelioma care?

The multidisciplinary approach to mesothelioma care involves a team of experts from various specialties working together to provide the best possible treatment.

What surgical options are available for mesothelioma?

The University of Maryland Greenebaum Cancer Center offers a range of surgical options for mesothelioma, including extrapleural pneumonectomy (EPP), pleurectomy/decortication (P/D), and video-assisted thoracoscopy (VATS).

What is radiation therapy for mesothelioma?

Radiation therapy uses high-energy radiation to kill cancer cells. The University of Maryland Greenebaum Cancer Center offers a range of radiation therapy options for mesothelioma, including intensity-modulated radiation therapy (IMRT), stereotactic body radiation therapy (SBRT), and brachytherapy.

What is chemotherapy for mesothelioma?

Chemotherapy is a systemic treatment that uses drugs to destroy cancer cells throughout the body. The University of Maryland Greenebaum Cancer Center offers a range of chemotherapy options for mesothelioma, including cisplatin, carboplatin, pemetrexed, and gemcitabine.

What is immunotherapy for mesothelioma?

Immunotherapy is a new and promising approach to mesothelioma treatment, which involves using the body’s own immune system to fight cancer cells. The University of Maryland Greenebaum Cancer Center offers a range of immunotherapy options for mesothelioma, including checkpoint inhibitors, CAR-T cell therapy, and cancer vaccines.

What are clinical trials for mesothelioma?

Clinical trials are research studies that involve testing new treatments for mesothelioma. The University of Maryland Greenebaum Cancer Center offers a range of clinical trials for mesothelioma, including trials for new chemotherapy drugs, immunotherapy treatments, and surgical techniques.

How can I participate in a clinical trial for mesothelioma?

If you are interested in participating in a clinical trial for mesothelioma, you should speak with your doctor or contact the University of Maryland Greenebaum Cancer Center directly.

What should I do if I have been diagnosed with mesothelioma?

If you have been diagnosed with mesothelioma, it is important to seek treatment from a team of experts who have experience in treating the disease. The University of Maryland Greenebaum Cancer Center offers a range of cutting-edge treatments for mesothelioma, and can provide the information and resources you need to navigate this complex disease.

Conclusion

Mesothelioma is a rare and aggressive cancer that presents a significant challenge for patients and healthcare professionals alike. The University of Maryland Greenebaum Cancer Center is at the forefront of research and clinical care for mesothelioma, offering a multidisciplinary team of experts, cutting-edge treatments, and innovative clinical trials. Whether you are a patient, caregiver, or healthcare professional, we hope that this guide has provided the information and resources you need to navigate this complex disease. We encourage you to take action and seek treatment from the experts at the University of Maryland Greenebaum Cancer Center.

Contact Us

If you have any questions or would like to schedule an appointment with the mesothelioma team at the University of Maryland Greenebaum Cancer Center, please contact us at 1-800-888-8823 or visit our website at www.umgcc.org.